MicroRNA-21 induces loss of 15-hydroxyprostaglandin dehydrogenase in early gastric tubular adenocarcinoma

15-hydroxyprostaglandin dehydrogenase (15-PGDH), the rate-limiting enzyme in prostaglandin E2 degradation, is decreased in gastric cancers and microRNA (miR)-21 is one of the regulators. We investigated the expression and regulation of 15-PGDH in eary gastric carcinogenesis utilizing endoscopic subm...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Park, Young Soo, Lee, Jeong Hoon, Jung, Deok-Beom, Kim, Han-Byul, Jung, Jin-Hak, Pak, Sehyung, Ryu, Yeon-Mi, Park, Hye Jin, Park, Yun-Yong, Jung, Hwoon-Yong, Myung, Seung-Jae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286338/
https://ncbi.nlm.nih.gov/pubmed/30531928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36139-z
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