Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study

BACKGROUND: Type-2 diabetes mellitus (T2DM) is a major health problem with increasing incidence, which severely impacts cardiovascular disease. Because T2DM is associated with altered gene expression and aberrant splicing, we hypothesized that dysregulations in splicing machinery could precede, cont...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Gahete, Manuel D., del Rio-Moreno, Mercedes, Camargo, Antonio, Alcala-Diaz, Juan F., Alors-Perez, Emilia, Delgado-Lista, Javier, Reyes, Oscar, Ventura, Sebastian, Perez-Martínez, Pablo, Castaño, Justo P., Lopez-Miranda, José, Luque, Raul M.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286259/
https://ncbi.nlm.nih.gov/pubmed/30446432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.056
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