Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study

BACKGROUND: Type-2 diabetes mellitus (T2DM) is a major health problem with increasing incidence, which severely impacts cardiovascular disease. Because T2DM is associated with altered gene expression and aberrant splicing, we hypothesized that dysregulations in splicing machinery could precede, cont...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EBioMedicine
Päätekijät: Gahete, Manuel D., del Rio-Moreno, Mercedes, Camargo, Antonio, Alcala-Diaz, Juan F., Alors-Perez, Emilia, Delgado-Lista, Javier, Reyes, Oscar, Ventura, Sebastian, Perez-Martínez, Pablo, Castaño, Justo P., Lopez-Miranda, José, Luque, Raul M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2018
Aiheet:
Research paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286259/
https://ncbi.nlm.nih.gov/pubmed/30446432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.056
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