Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study

BACKGROUND: Type-2 diabetes mellitus (T2DM) is a major health problem with increasing incidence, which severely impacts cardiovascular disease. Because T2DM is associated with altered gene expression and aberrant splicing, we hypothesized that dysregulations in splicing machinery could precede, cont...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Gahete, Manuel D., del Rio-Moreno, Mercedes, Camargo, Antonio, Alcala-Diaz, Juan F., Alors-Perez, Emilia, Delgado-Lista, Javier, Reyes, Oscar, Ventura, Sebastian, Perez-Martínez, Pablo, Castaño, Justo P., Lopez-Miranda, José, Luque, Raul M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
Soggetti:
Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286259/
https://ncbi.nlm.nih.gov/pubmed/30446432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.056
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