A Malaria Vaccine Adjuvant Based on Recombinant Antigen Binding to Liposomes

Pfs25 is a malaria transmission-blocking vaccine antigen candidate, but its apparently limited immunogenicity in humans has hindered clinical development. Here, we show that recombinant, his-tagged Pfs25 can be mixed at the time of immunization with pre-formed liposomes containing cobalt-porphyrin-p...

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Publicado en:Nat Nanotechnol
Autores principales: Huang, Wei-Chiao, Deng, Bingbing, Lin, Cuiyan, Carter, Kevin A., Geng, Jumin, Razi, Aida, He, Xuedan, Chitgupi, Upendra, Federizon, Jasmin, Sun, Boyang, Long, Carole A., Ortega, Joaquin, Dutta, Sheetij, King, C. Richter, Miura, Kazutoyo, Lee, Shwu-Maan, Lovell, Jonathan F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286227/
https://ncbi.nlm.nih.gov/pubmed/30297818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-018-0271-3
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