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Eculizumab Bridging Before Bone Marrow Transplant for Marrow Failure Disorders is Safe and Does Not Limit Engraftment

BACKGROUND. Paroxysmal nocturnal hemoglobinuria (PNH) often develops secondary to other bone marrow failure (BMF) disorders, especially aplastic anemia (AA). Patients with the AA/PNH syndrome may require treatment with both eculizumab to reduce intravascular hemolysis and the risk of thrombosis and...

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Vydáno v:Biol Blood Marrow Transplant
Hlavní autoři: DeZern, Amy E., Jones, Richard J., Brodsky, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286212/
https://ncbi.nlm.nih.gov/pubmed/30055352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2018.07.032
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