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Human COX7A2L Regulates Complex III Biogenesis and Promotes Supercomplex Organization Remodeling without Affecting Mitochondrial Bioenergetics
The mitochondrial respiratory chain is organized in a dynamic set of supercomplexes (SCs). The COX7A2L protein is essential for mammalian SC III(2)+IV assembly. However, its function in respirasome (SCs I+III(2)+IV(n)) biogenesis remains controversial. To unambiguously determine the COX7A2L role, we...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Rep |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6286155/ https://ncbi.nlm.nih.gov/pubmed/30428348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.058 |
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