Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease

Alterations in the mechanical properties of erythrocytes occurring in inflammatory and hematologic disorders such as sickle cell disease (SCD) and malaria often lead to increased endothelial permeability, haemolysis, and microvascular obstruction. However, the associations among these pathological p...

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Pubblicato in:Nat Biomed Eng
Autori principali: Qiu, Yongzhi, Ahn, Byungwook, Sakurai, Yumiko, Hansen, Caroline, Tran, Reginald, Mimche, Patrice N., Mannino, Robert, Ciciliano, Jordan C., Lamb, Tracey J., Joiner, Clinton H., Ofori-Acquah, Solomon F., Lam, Wilbur A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286070/
https://ncbi.nlm.nih.gov/pubmed/30533277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-018-0224-z
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