Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease

Alterations in the mechanical properties of erythrocytes occurring in inflammatory and hematologic disorders such as sickle cell disease (SCD) and malaria often lead to increased endothelial permeability, haemolysis, and microvascular obstruction. However, the associations among these pathological p...

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Bibliographic Details
Published in:Nat Biomed Eng
Main Authors: Qiu, Yongzhi, Ahn, Byungwook, Sakurai, Yumiko, Hansen, Caroline, Tran, Reginald, Mimche, Patrice N., Mannino, Robert, Ciciliano, Jordan C., Lamb, Tracey J., Joiner, Clinton H., Ofori-Acquah, Solomon F., Lam, Wilbur A.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286070/
https://ncbi.nlm.nih.gov/pubmed/30533277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-018-0224-z
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