Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease

Alterations in the mechanical properties of erythrocytes occurring in inflammatory and hematologic disorders such as sickle cell disease (SCD) and malaria often lead to increased endothelial permeability, haemolysis, and microvascular obstruction. However, the associations among these pathological p...

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Udgivet i:Nat Biomed Eng
Main Authors: Qiu, Yongzhi, Ahn, Byungwook, Sakurai, Yumiko, Hansen, Caroline, Tran, Reginald, Mimche, Patrice N., Mannino, Robert, Ciciliano, Jordan C., Lamb, Tracey J., Joiner, Clinton H., Ofori-Acquah, Solomon F., Lam, Wilbur A.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286070/
https://ncbi.nlm.nih.gov/pubmed/30533277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-018-0224-z
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