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Characterizing changes in glucocorticoid receptor internalization in the fear circuit in an animal model of post traumatic stress disorder

Glucocorticoid receptors (GRs) shuttle from the cytoplasm (cy) to the nucleus (nu) when bound with glucocorticoids (i.e. GR internalization) and alter transcriptional activity. GR activation within the fear circuit has been implicated in fear memory and post traumatic stress disorder (PTSD). However...

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Publicado en:PLoS One
Autores principales: Moulton, Emily, Chamness, Marisa, Knox, Dayan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286002/
https://ncbi.nlm.nih.gov/pubmed/30532228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205144
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