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Characterizing changes in glucocorticoid receptor internalization in the fear circuit in an animal model of post traumatic stress disorder

Glucocorticoid receptors (GRs) shuttle from the cytoplasm (cy) to the nucleus (nu) when bound with glucocorticoids (i.e. GR internalization) and alter transcriptional activity. GR activation within the fear circuit has been implicated in fear memory and post traumatic stress disorder (PTSD). However...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Moulton, Emily, Chamness, Marisa, Knox, Dayan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286002/
https://ncbi.nlm.nih.gov/pubmed/30532228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205144
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