A Mendelian randomization study of circulating uric acid and type 2 diabetes

We aimed to investigate the causal effect of circulating uric acid concentrations on type 2 diabetes risk. A Mendelian randomization study was performed using a genetic score with 24 uric acid associated loci. We used data of the EPIC-InterAct case-cohort study, comprising 24,265 individuals of Euro...

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Pubblicato in:Diabetes
Autori principali: Sluijs, Ivonne, Holmes, Michael V, van der Schouw, Yvonne T, Beulens, Joline WJ, Asselbergs, Folkert W, Huerta, José María, Palmer, Tom M, Arriola, Larraitz, Balkau, Beverley, Barricarte, Aurelio, Boeing, Heiner, Clavel-Chapelon, Françoise, Fagherazzi, Guy, Franks, Paul W, Gavrila, Diana, Kaaks, Rudolf, Khaw, Kay Tee, Kühn, Tilman, Molina-Montes, Esther, Mortensen, Lotte Maxild, Nilsson, Peter M, Overvad, Kim, Palli, Domenico, Panico, Salvatore, Quirós, J. Ramón, Rolandsson, Olov, Sacerdote, Carlotta, Sala, Núria, Schmidt, Julie A, Scott, Robert A, Sieri, Sabina, Slimani, Nadia, Spijkerman, Annemieke MW, Tjonneland, Anne, Travis, Ruth C, Tumino, Rosario, van der A, Daphne L, Sharp, Stephen J, Forouhi, Nita G, Langenberg, Claudia, Riboli, Elio, Wareham, Nicholas J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284788/
https://ncbi.nlm.nih.gov/pubmed/25918230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0742
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