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Natural product pectolinarigenin inhibits proliferation, induces apoptosis, and causes G2/M phase arrest of HCC via PI3K/AKT/mTOR/ERK signaling pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by considerable phenotypic and molecular heterogeneity, but the overall survival of HCC patients remains extremely poor. Thus, novel and efficient alternatives to antitumor agents are urgently needed. Pectolinarigenin, a flavonoid compound...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Wu, Tianchun, Dong, Xiaogang, Yu, Dongdong, Shen, Zhenhua, Yu, Jinbei, Yan, Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284530/
https://ncbi.nlm.nih.gov/pubmed/30584322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S186186
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