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Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade

Emerging evidence suggests a role for radiation in eliciting anti‐tumour immunity. We aimed to investigate the role of macrophages in modulating the immune response to radiation. Irradiation to murine tumours generated from colorectal (MC38) and pancreatic (KPC) cell lines induced colony‐stimulating...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Jones, Keaton I, Tiersma, Jiske, Yuzhalin, Arseniy E, Gordon‐Weeks, Alex N, Buzzelli, Jon, Im, Jae Hong, Muschel, Ruth J
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284388/
https://ncbi.nlm.nih.gov/pubmed/30442705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809342
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