Radiation combined with macrophage depletion promotes adaptive immunity and potentiates checkpoint blockade

Emerging evidence suggests a role for radiation in eliciting anti‐tumour immunity. We aimed to investigate the role of macrophages in modulating the immune response to radiation. Irradiation to murine tumours generated from colorectal (MC38) and pancreatic (KPC) cell lines induced colony‐stimulating...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Jones, Keaton I, Tiersma, Jiske, Yuzhalin, Arseniy E, Gordon‐Weeks, Alex N, Buzzelli, Jon, Im, Jae Hong, Muschel, Ruth J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284388/
https://ncbi.nlm.nih.gov/pubmed/30442705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809342
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