Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

Obesity-associated metabolic alterations are closely linked to low-grade inflammation in peripheral organs, in which macrophages play a central role. Using genetic labeling of myeloid lineage cells, we show that hypothalamic macrophages normally reside in the perivascular area and circumventricular...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Lee, Chan Hee, Kim, Hyo Jin, Lee, Yong-Soo, Kang, Gil Myoung, Lim, Hyo Sun, Lee, Seung-hwan, Song, Do Kyeong, Kwon, Obin, Hwang, Injae, Son, Myeongjoo, Byun, Kyunghee, Sung, Young Hoon, Kim, Seyun, Kim, Jae Bum, Choi, Eun Young, Kim, Young-Bum, Kim, Keetae, Kweon, Mi-Na, Sohn, Jong-Woo, Kim, Min-Seon
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284237/
https://ncbi.nlm.nih.gov/pubmed/30355499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.070
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