Phlorotannins from Ecklonia cava Attenuates Palmitate-Induced Endoplasmic Reticulum Stress and Leptin Resistance in Hypothalamic Neurons

Leptin resistance in the hypothalamus has an essential role in obesity. Saturated fatty acids such as palmitate bind to Toll-like receptor 4 (TLR4) and lead to endoplasmic reticulum (ER) stress and leptin resistance. In this study, we evaluated whether extracts of Ecklonia cava would attenuate the E...

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Veröffentlicht in:Mar Drugs
Hauptverfasser: Oh, Seyeon, Son, Myeongjoo, Choi, Junwon, Choi, Chang Hu, Park, Kook Yang, Son, Kuk Hui, Byun, Kyunghee
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835517/
https://ncbi.nlm.nih.gov/pubmed/31600939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17100570
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