TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascade

Transforming growth factor (TGF)-β signaling is increasingly recognized as a key driver in cancer. In progressive cancer tissues, TGF-β promotes tumor formation, and its increased expression often correlates with cancer malignancy. In this study, we utilized adenoviruses expressing short hairpin RNA...

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I publikationen:Exp Mol Med
Huvudupphovsmän: Han, Zhezhu, Kang, Dongxu, Joo, Yeonsoo, Lee, Jihyun, Oh, Geun-Hyeok, Choi, Soojin, Ko, Suwan, Je, Suyeon, Choi, Hye Jin, Song, Jae J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283885/
https://ncbi.nlm.nih.gov/pubmed/30523245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0189-8
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