Loss of interneurons and disruption of perineuronal nets in the cerebral cortex following hypoxia-ischaemia in near-term fetal sheep

Hypoxia-ischaemia (HI) in term infants is a common cause of brain injury and neurodevelopmental impairment. Development of gamma-aminobutyric acid (GABA)ergic circuitry in the cerebral cortex is a critical event in perinatal brain development. Perineuronal nets (PNNs) are specialised extracellular m...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Fowke, Tania M., Galinsky, Robert, Davidson, Joanne O., Wassink, Guido, Karunasinghe, Rashika N., Prasad, Jaya D., Bennet, Laura, Gunn, Alistair J., Dean, Justin M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283845/
https://ncbi.nlm.nih.gov/pubmed/30523273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36083-y
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