Irisin protects heart against ischemia-reperfusion injury through a SOD2-dependent mitochondria mechanism

Irisin, a muscle-origin protein derived from the extracellular domain of the fibronectin domain-containing 5 protein (FNDC5), has been shown to modulate mitochondria welfare through paracrine action. Here we test the hypothesis that irisin contributes to cardioprotection after myocardial infarction...

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Detalhes bibliográficos
Publicado no:J Cardiovasc Pharmacol
Main Authors: Wang, Zhen, Chen, Ken, Han, Yu, Zhu, Hua, Zhou, Xinyu, Tan, Tao, Zeng, Jing, Zhang, Jun, Liu, Yukai, Li, Yu, Yao, Yonggang, Yi, Jianxun, He, Duofen, Zhou, Jingsong, Ma, Jianjie, Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283696/
https://ncbi.nlm.nih.gov/pubmed/29979350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000608
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