Stimulation of Dopamine D(3) Receptor Attenuates Renal Ischemia/Reperfusion Injury via Increased Linkage with Gα12

BACKGROUND: Renal ischemia reperfusion (I/R) injury causes renal tubular necrosis, apoptosis, and inflammation leading to acute renal dysfunction. Recent studies have revealed that deletion of Gα12 mitigates the renal damage due to I/R injury. Our previous study showed that activation of D(3)R incre...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: Wang, Zhen, Guan, Weiwei, Han, Yu, Ren, Hongmei, Tang, Xiaofeng, Zhang, Hui, Liu, Yukai, Fu, Jinjuan, He, Duofen, Asico, Laureano D., Jose, Pedro A., Zhou, Lin, Chen, Liyong, Zeng, Chunyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618723/
https://ncbi.nlm.nih.gov/pubmed/25989500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000000762
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