Microglia changes associated to Alzheimer’s disease pathology in aged chimpanzees

In Alzheimer’s disease (AD), the brain’s primary immune cells microglia become activated and are found in close apposition to amyloid beta (Aβ) protein plaques and neurofibrillary tangles (NFT). The present study evaluated microglia density and morphology in a large group of aged chimpanzees (n = 20...

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Udgivet i:J Comp Neurol
Main Authors: Edler, Melissa K., Sherwood, Chet C., Meindl, Richard S., Munger, Emily, Hopkins, William D., Ely, John J., Erwin, Joseph M., Perl, Daniel P., Mufson, Elliott J., Hof, Patrick R., Raghanti, Mary Ann
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283685/
https://ncbi.nlm.nih.gov/pubmed/30069930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.24484
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