Aged chimpanzees exhibit pathologic hallmarks of Alzheimer’s disease

Alzheimer’s disease (AD) is a uniquely human brain disorder characterized by the accumulation of amyloid beta protein (Aβ) into extracellular plaques, neurofibrillary tangles (NFT) made from intracellular, abnormally phosphorylated tau, and selective neuronal loss. We analyzed a large group of aged...

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Bibliografiske detaljer
Udgivet i:Neurobiol Aging
Main Authors: Edler, Melissa K., Sherwood, Chet C., Meindl, Richard S., Hopkins, William D., Ely, John J., Erwin, Joseph M., Mufson, Elliott J., Hof, Patrick R., Raghanti, Mary Ann
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343147/
https://ncbi.nlm.nih.gov/pubmed/28888720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.07.006
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