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The impact of a fine-scale population stratification on rare variant association test results

Population stratification is a well-known confounding factor in both common and rare variant association analyses. Rare variants tend to be more geographically clustered than common variants, because of their more recent origin. However, it is not yet clear if population stratification at a very fin...

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Vydáno v:PLoS One
Hlavní autoři: Persyn, Elodie, Redon, Richard, Bellanger, Lise, Dina, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283567/
https://ncbi.nlm.nih.gov/pubmed/30521541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207677
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