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Study of tau pathology in male rTg4510 mice fed with a curcumin derivative Shiga-Y5

Intracellular inclusions of aggregated tau appear in neurons and glial cells in a range of neurodegenerative diseases known as tauopathies. Inhibition of pathological changes in tau is a therapeutic target for tauopathy. We recently synthesized a novel curcumin derivative, named Shiga-Y5, and showed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yanagisawa, Daijiro, Hamezah, Hamizah Shahirah, Durani, Lina Wati, Taguchi, Hiroyasu, Tooyama, Ikuo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283544/
https://ncbi.nlm.nih.gov/pubmed/30521594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208440
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