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Phosphate effect on filipin production and morphological differentiation in Streptomyces filipinensis and the role of the PhoP transcription factor

The biosynthesis of the antifungal filipin in Streptomyces filipinensis is very sensitive to phosphate regulation. Concentrations as low as 2.5 mM block filipin production. This effect is, at least in part, produced by repression of the transcription of most filipin biosynthetic genes. The role of t...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Barreales, Eva G., Payero, Tamara D., de Pedro, Antonio, Aparicio, Jesús F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283541/
https://ncbi.nlm.nih.gov/pubmed/30521601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208278
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