Hepatic Mitochondrial Defects in a Nonalcoholic Fatty Liver Disease Mouse Model Are Associated with Increased Degradation of Oxidative Phosphorylation Subunits

Nonalcoholic fatty liver disease (NAFLD) is associated with hepatic mitochondrial dysfunction characterized by reduced ATP synthesis. We applied the (2)H(2)O-metabolic labeling approach to test the hypothesis that the reduced stability of oxidative phosphorylation proteins contributes to mitochondri...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Proteomics
Egile Nagusiak: Lee, Kwangwon, Haddad, Andrew, Osme, Abdullah, Kim, Chunki, Borzou, Ahmad, Ilchenko, Sergei, Allende, Daniela, Dasarathy, Srinivasan, McCullough, Arthur, Sadygov, Rovshan G., Kasumov, Takhar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283295/
https://ncbi.nlm.nih.gov/pubmed/30171159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA118.000961
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