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Ras-Dependent Cell Fate Decisions Are Reinforced by the RAP-1 Small GTPase in Caenorhabditis elegans

The notoriety of the small GTPase Ras as the most mutated oncoprotein has led to a well-characterized signaling network largely conserved across metazoans. Yet the role of its close relative Rap1 (Ras Proximal), which shares 100% identity between their core effector binding sequences, remains unclea...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Rasmussen, Neal R., Dickinson, Daniel J., Reiner, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283165/
https://ncbi.nlm.nih.gov/pubmed/30257933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301601
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