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Ras and Rap1: A Tale of Two GTPases

Ras oncoproteins play pivotal roles in both the development and maintenance of many tumor types. Unfortunately, these proteins are difficult to directly target using traditional pharmacological strategies, in part due to their lack of obvious binding pockets or allosteric sites. This obstacle has dr...

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Bibliografische gegevens
Gepubliceerd in:Semin Cancer Biol
Hoofdauteurs: Shah, Seema, Brock, Ethan J., Ji, Kyungmin, Mattingly, Raymond R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170734/
https://ncbi.nlm.nih.gov/pubmed/29621614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2018.03.005
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