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Ras and Rap1: A Tale of Two GTPases
Ras oncoproteins play pivotal roles in both the development and maintenance of many tumor types. Unfortunately, these proteins are difficult to directly target using traditional pharmacological strategies, in part due to their lack of obvious binding pockets or allosteric sites. This obstacle has dr...
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| Veröffentlicht in: | Semin Cancer Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6170734/ https://ncbi.nlm.nih.gov/pubmed/29621614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2018.03.005 |
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