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Bidirectional regulation of adenosine 5′‐monophosphate–activated protein kinase activity by berberine and metformin in response to changes in ambient glucose concentration

Both berberine and metformin are well‐known antihyperglycemic agents for diabetes treatment. Adenosine monophosphate (AMP)‐activated protein kinase (AMPK) activation is often considered as the most important molecular mechanism although the mechanism has been challenged recently. Up to now, when the...

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Vydáno v:J Cell Biochem
Hlavní autoři: Xiao, Yuanyuan, Xu, Miao, Alimujiang, Miriayi, Bao, Yuqian, Wei, Li, Yin, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282525/
https://ncbi.nlm.nih.gov/pubmed/30129983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.27312
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