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Homotypic and Heterotypic Activation of the Notch Pathway in Multiple Myeloma–Enhanced Angiogenesis: A Novel Therapeutic Target?()

Interactions of multiple myeloma (MM) cells with endothelial cells (ECs) enhance angiogenesis and MM progression. Here, we investigated the role of Notch signaling in the cross talk between ECs and MM cells enabling angiogenesis. MMECs showed higher expression of Jagged1/2 ligands, of activated Notc...

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Bibliografische gegevens
Gepubliceerd in:Neoplasia
Hoofdauteurs: Saltarella, Ilaria, Frassanito, Maria Antonia, Lamanuzzi, Aurelia, Brevi, Arianna, Leone, Patrizia, Desantis, Vanessa, Di Marzo, Lucia, Bellone, Matteo, Derudas, Daniele, Ribatti, Domenico, Chiaramonte, Raffaella, Palano, Maria Teresa, Neri, Antonino, Mariggiò, Maria Addolorata, Fumarulo, Ruggiero, Dammacco, Franco, Racanelli, Vito, Vacca, Angelo, Ria, Roberto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Neoplasia Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282459/
https://ncbi.nlm.nih.gov/pubmed/30529074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.10.011
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