Homotypic and Heterotypic Activation of the Notch Pathway in Multiple Myeloma–Enhanced Angiogenesis: A Novel Therapeutic Target?()

Interactions of multiple myeloma (MM) cells with endothelial cells (ECs) enhance angiogenesis and MM progression. Here, we investigated the role of Notch signaling in the cross talk between ECs and MM cells enabling angiogenesis. MMECs showed higher expression of Jagged1/2 ligands, of activated Notc...

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Bibliografiska uppgifter
I publikationen:Neoplasia
Huvudupphovsmän: Saltarella, Ilaria, Frassanito, Maria Antonia, Lamanuzzi, Aurelia, Brevi, Arianna, Leone, Patrizia, Desantis, Vanessa, Di Marzo, Lucia, Bellone, Matteo, Derudas, Daniele, Ribatti, Domenico, Chiaramonte, Raffaella, Palano, Maria Teresa, Neri, Antonino, Mariggiò, Maria Addolorata, Fumarulo, Ruggiero, Dammacco, Franco, Racanelli, Vito, Vacca, Angelo, Ria, Roberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press 2018
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Original article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282459/
https://ncbi.nlm.nih.gov/pubmed/30529074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.10.011
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