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Juvenile cerebral ischemia reveals age-dependent BDNF–TrkB signaling changes: Novel mechanism of recovery and therapeutic intervention

Global ischemia in childhood often leads to poor neurologic outcomes, including learning and memory deficits. Using our novel model of childhood cardiac arrest/cardiopulmonary resuscitation (CA/CPR), we investigate the mechanism of ischemia-induced cognitive deficits and recovery. Memory is impaired...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cereb Blood Flow Metab
Hauptverfasser: Dietz, Robert M, Orfila, James E, Rodgers, Krista M, Patsos, Olivia P, Deng, Guiying, Chalmers, Nicholas, Quillinan, Nidia, Traystman, Richard J, Herson, Paco S
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282214/
https://ncbi.nlm.nih.gov/pubmed/29611441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18766421
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