Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular toxicity

Chemically-induced vascular toxicity during embryonic development may cause a wide range of adverse effects. To identify putative vascular disrupting chemicals (pVDCs), a predictive pVDC signature was constructed from 124 U.S. EPA ToxCast high-throughput screening (HTS) assays and used to rank 1060...

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Detalhes bibliográficos
Publicado no:Reprod Toxicol
Main Authors: Tal, Tamara, Kilty, Claire, Smith, Andrew, LaLone, Carlie, Kennedy, Brendán, Tennant, Alan, McCollum, Catherine W., Bondesson, Maria, Knudsen, Thomas, Padilla, Stephanie, Kleinstreuer, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282194/
https://ncbi.nlm.nih.gov/pubmed/28007540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2016.12.004
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