Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells

To identify vascular disruptor compounds (VDCs), this study utilized an in vivo zebrafish embryo vascular model in conjunction with a mouse endothelial cell model to screen a subset of the U.S. Environmental Protection Agency (EPA) ToxCast Phase I chemical inventory. In zebrafish, 161 compounds were...

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Detalhes bibliográficos
Publicado no:Reprod Toxicol
Main Authors: McCollum, Catherine W., Vancells, Javier Conde, Hans, Charu, Vazquez-Chantada, Mercedes, Kleinstreuer, Nicole, Tal, Tamara, Knudsen, Thomas, Shah, Shishir S., Merchant, Fatima A., Finnell, Richard H., Gustafsson, Jan-Åke, Cabrera, Robert, Bondesson, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5425326/
https://ncbi.nlm.nih.gov/pubmed/27838387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2016.11.005
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