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Glycosylation promotes random coil to helix transition in a region of a protist Skp1 associated with F-box binding

Cullin-Ring-Ligases mediate protein polyubiquitination, a signal for degradation in the 26S-proteasome. The CRL1 class consists of Skp1/cullin-1/F-box protein/Rbx1 (SCF) complexes that cyclically associate with ubiquitin-E2 to build the polyubiquitin chain. Within the SCF complex, the 162-amino acid...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Xu, Xianzhong, Eletsky, Alexander, Sheikh, M. Osman, Prestegard, James H., West, Christopher M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282176/
https://ncbi.nlm.nih.gov/pubmed/29251491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01033
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