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Non-invasive delivery of an α-synuclein gene silencing vector with MR-guided focused ultrasound
BACKGROUND: The characteristic progression of Lewy pathology in Parkinson’s disease likely involves intercellular exchange and accumulation of misfolded α-synuclein amplified by a prion-like self-templating mechanism. Silencing of the α-synuclein gene could provide long-lasting disease modifying ben...
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| Udgivet i: | Mov Disord |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6282171/ https://ncbi.nlm.nih.gov/pubmed/30264465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.101 |
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