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Non-invasive delivery of an α-synuclein gene silencing vector with MR-guided focused ultrasound

BACKGROUND: The characteristic progression of Lewy pathology in Parkinson’s disease likely involves intercellular exchange and accumulation of misfolded α-synuclein amplified by a prion-like self-templating mechanism. Silencing of the α-synuclein gene could provide long-lasting disease modifying ben...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mov Disord
Egile Nagusiak: Xhima, Kristiana, Nabbouh, Fadl, Hynynen, Kullervo, Aubert, Isabelle, Tandon, Anurag
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282171/
https://ncbi.nlm.nih.gov/pubmed/30264465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.101
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