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Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining
Drug repurposing aims to find novel indications of clinically used or experimental drugs. Because drug data already exist, drug repurposing may save time and cost, and bypass safety concerns. Polypharmacology, one drug with multiple targets, serves as a basis for drug repurposing. Large-scale databa...
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| Udgivet i: | R Soc Open Sci |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281908/ https://ncbi.nlm.nih.gov/pubmed/30564416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.181321 |
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