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Persistent Elevations in Circulating INS DNA Among Subjects with Longstanding Type 1 Diabetes
AIMS: DNA release by dying β cells leads to increased circulating levels of unmethylated preproinsulin (INS) DNA. Consistent with large-scale β cell destruction, this biomarker is elevated before and at the time of type 1 diabetes (T1D) onset. We measured serum INS DNA to evaluate whether β cells co...
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| Veröffentlicht in: | Diabetes Obes Metab |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281817/ https://ncbi.nlm.nih.gov/pubmed/30073765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.13489 |
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