Association Analysis of NLRP3 Inflammation-Related Gene Promotor Methylation as Well as Mediating Effects on T2DM and Vascular Complications in a Southern Han Chinese Population

Objective: To explore the association between the methylation levels in the promoter regions of the NLRP3, AIM2, and ASC genes and T2DM and its vascular complications in a Southern Han Chinese population and further analyze their interaction and mediating effects with environmental factors in T2DM....

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Zhou, Zixing, Wang, Lijun, Wen, Zihao, Zheng, Shaoling, Ye, Xiaohong, Liu, Dandan, Wu, Jing, Zou, Xiaoqian, Liu, Yumei, Wang, Yao, Dong, Shirui, Huang, Xiuxia, Du, Xiuben, Zhu, Kehui, Chen, Xiaojing, Huang, Shiqi, Zeng, Chengli, Han, Yajing, Zhang, Baohuan, Nie, Lihong, Yang, Guang, Jing, Chunxia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281743/
https://ncbi.nlm.nih.gov/pubmed/30555415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2018.00709
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