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Identification of genetic variations in Necator americanus through resequencing by whole genome amplification

OBJECTIVE: To describe a new strategy for the whole genome resequencing of small parasite samples. METHODS: Whole genome resequencing was based on a multiple displacement amplification (MDA) method. Sequencing reads were aligned with the reference genome, and a Bayesian model was used to calculate g...

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Detalhes bibliográficos
Publicado no:J Int Med Res
Main Authors: Liu, Yumei, Liu, Hongxuan, Xie, Yuefeng, Zhang, Baohuan, Zou, Xiaoqian, Ou, Meiling, Ye, Xiaohong, Han, Yajing, Wu, Jing, Chen, Xiaojing, Dong, Shirui, Zhu, Kehui, Guo, Congcong, Wang, Penghua, Zhai, Hening, Jing, Chunxia, Yang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753555/
https://ncbi.nlm.nih.gov/pubmed/31331217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060519862069
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