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Inactivation of Lon protease reveals a link between mitochondrial unfolded protein stress and mitochondrial translation inhibition

The mitochondrial Unfolded Protein Response (UPR(mt)) pathway confers protection from misfolded and aggregated proteins by activating factors that promote protein folding and degradation. Our recent work on Lon protease, a member of the mitochondrial ATPase Associated with diverse cellular Activitie...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Pareek, Gautam, Pallanck, Leo J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281655/
https://ncbi.nlm.nih.gov/pubmed/30518747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1213-6
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