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Nutritional stress reprograms dedifferention in glioblastoma multiforme driven by PTEN/Wnt/Hedgehog axis: a stochastic model of cancer stem cells

The emergence and maintenance of cancer stem-like cells (CSCs) are usually governed by tumor niche. Tumor niche always provides metabolic challenges to cancer cells and CSCs mostly because of tissue hypoxia. However, the role of micro-environmental nutritional stress (NS) in dedifferentiation of can...

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Bibliografiska uppgifter
I publikationen:Cell Death Discov
Huvudupphovsmän: Mondal, Susmita, Bhattacharya, Kaushik, Mandal, Chitra
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281623/
https://ncbi.nlm.nih.gov/pubmed/30534418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0126-6
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