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A semi-supervised approach for predicting cell-type specific functional consequences of non-coding variation using MPRAs
Predicting the functional consequences of genetic variants in non-coding regions is a challenging problem. We propose here a semi-supervised approach, GenoNet, to jointly utilize experimentally confirmed regulatory variants (labeled variants), millions of unlabeled variants genome-wide, and more tha...
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| Izdano u: | Nat Commun |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281617/ https://ncbi.nlm.nih.gov/pubmed/30518757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07349-w |
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