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Finding combinatorial histone code by semi-supervised biclustering

BACKGROUND: Combinatorial histone modification is an important epigenetic mechanism for regulating chromatin state and gene expression. Given the rapid accumulation of genome-wide histone modification maps, there is a pressing need for computational methods capable of joint analysis of multiple maps...

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Detalhes bibliográficos
Main Authors: Teng, Li, Tan, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3443427/
https://ncbi.nlm.nih.gov/pubmed/22759587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-301
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