Variant of SNP rs1317082 at CCSlnc362 (RP11-362K14.5) creates a binding site for miR-4658 and diminishes the susceptibility to CRC

Genome-wide association studies (GWAS) have identified several loci harboring variants that affected the risk of colorectal cancer; however, the specific mechanisms by which germline variation influenced the tumorigenesis of colorectal cancer (CRC) remains unrevealed. We found the T>C variant of...

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Publicado no:Cell Death Dis
Main Authors: Shen, Chaoqin, Yan, Tingting, Wang, Zhenhua, Su, Heng-chuan, Zhu, Xiaoqiang, Tian, Xianglong, Fang, Jing-Yuan, Chen, Haoyan, Hong, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281592/
https://ncbi.nlm.nih.gov/pubmed/30518759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1222-5
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