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Purified Protein Delivery to Activate an Epigenetically Silenced Allele in Mouse Brain

The ability to activate or repress specific genes in the brain could have a tremendous impact for understanding and treating neurological disorders. Artificial transcription factors based on zinc finger, TALE, and CRISPR/Cas9 programmable DNA-binding platforms have been widely used to regulate the e...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Pyles, Benjamin, Bailus, Barbara J., O’Geen, Henriette, Segal, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281562/
https://ncbi.nlm.nih.gov/pubmed/29524138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7774-1_12
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