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emClarity: Software for High Resolution Cryo-electron Tomography and Sub-tomogram Averaging
Macromolecular complexes are intrinsically flexible and often challenging to purify for structure determination by single particle cryoEM. Such complexes may be studied using cryo-electron tomography combined with sub-tomogram alignment and classification, which in exceptional cases reaches sub-nano...
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| Publié dans: | Nat Methods |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281437/ https://ncbi.nlm.nih.gov/pubmed/30349041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0167-z |
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