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emClarity: Software for High Resolution Cryo-electron Tomography and Sub-tomogram Averaging

Macromolecular complexes are intrinsically flexible and often challenging to purify for structure determination by single particle cryoEM. Such complexes may be studied using cryo-electron tomography combined with sub-tomogram alignment and classification, which in exceptional cases reaches sub-nano...

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Pubblicato in:Nat Methods
Autori principali: Himes, Benjamin A., Zhang, Peijun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281437/
https://ncbi.nlm.nih.gov/pubmed/30349041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0167-z
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