Human liver stem cell-derived extracellular vesicles enhance cancer stem cell sensitivity to tyrosine kinase inhibitors through Akt/mTOR/PTEN combined modulation

It is well recognized that Cancer Stem Cells (CSCs) sustain the initiation, the maintenance and the recurrence of tumors. We previously reported that extracellular vesicles (EVs) derived from human liver stem cells (HLSCs) were able to limit tumor development. In this study, we evaluated whether EV...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Fonsato, Valentina, De Lena, Michela, Tritta, Stefania, Brossa, Alessia, Calvetti, Ruggero, Tetta, Ciro, Camussi, Giovanni, Bussolati, Benedetta
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281417/
https://ncbi.nlm.nih.gov/pubmed/30546834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26319
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