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Human liver stem cell-derived extracellular vesicles enhance cancer stem cell sensitivity to tyrosine kinase inhibitors through Akt/mTOR/PTEN combined modulation

It is well recognized that Cancer Stem Cells (CSCs) sustain the initiation, the maintenance and the recurrence of tumors. We previously reported that extracellular vesicles (EVs) derived from human liver stem cells (HLSCs) were able to limit tumor development. In this study, we evaluated whether EV...

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書誌詳細
出版年:Oncotarget
主要な著者: Fonsato, Valentina, De Lena, Michela, Tritta, Stefania, Brossa, Alessia, Calvetti, Ruggero, Tetta, Ciro, Camussi, Giovanni, Bussolati, Benedetta
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281417/
https://ncbi.nlm.nih.gov/pubmed/30546834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26319
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